Engineered cell therapies rely on synthetic receptors to transduce external signals into intracellular responses. The precise relationship between receptor structure and function remains poorly ...

Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...

Cellular therapies, including chimeric antigen receptor T-cell therapy and bispecific antibodies (BsAbs), have revolutionized the treatment of various B-cell non-Hodgkin lymphomas. A number of agents ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of ...

The authors also resolved the structure of the Noelin 1-GluA1/A4 complex, and demonstrated that Noelin 1 (Noe 1) specifically binds to the GluA4 subunit at the B and D positions.

New synthetic biosensors developed by Professor Josh Leonard give immune cells the ability to read their environment and act ...

Acute kidney injury (AKI) is a severe renal disorder affecting approximately 10%-15% of hospitalized patients and up to 50% ...

"Hormone cycles shape the structure and function of key memory regions in the brain." ScienceDaily. ScienceDaily, 13 May 2025. <www.sciencedaily.com / releases / 2025 / 05 / 250513150241.htm>.