excessive aldosterone secretion — Starting dosage is 100 mg to 400 mg daily in preparation for surgery. If you cannot have surgery, your doctor may prescribe the lowest effective dose of this ...
The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well-treated, ...
b Due to production of non-aldosterone mineralocorticoids ... e Acquired forms due to either licorice ingestion or ectopic ACTH secretion. f Due to increased activity of sodium channels.
Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...
Sodium reabsorption is mainly controlled by aldosterone, a steroid hormone synthesized in the zona glomerulosa of the adrenal gland, secondary to renin stimulation via angiotensin II and to ...
Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally, when ...
Elevated aldosterone stimulates sodium reabsorption ... This mechanism results in increased potassium and hydrogen ion secretion through the urine, and a decrease in the protein or channel ...