The Pittsburgh Pirates saw no success hitting in their series finale vs. the San Diego Padres at PNC Park, suffering a 4-0 shutout and a series sweep. The Pirates have lost an MLB-leading six shutout games this season and had two this homestand,

Pregame analysis and predictions of the San Diego Padres vs. Pittsburgh Pirates MLB game to be played on May 4, 2025 on ESPN.

Bouncing back from the road four-game sweep to the Mets by winning the series at home, the Cardinals hope to do the same to the Pirates. The Pirates have not been doing well lately, although they’ve only played good teams.

Preview the May 4 matchup between the Pittsburgh Pirates and San Diego Padres with odds over/under, game spread, betting lines and more.

The Pirates are 1-5 in the last six games coming off back-to-back lost series against the Cubs and Dodgers. The Padres have won back-to-back games after four consecutive losses, so the two are trending in different directions.

The Pittsburgh Pirates play the second game of a 3-game set at Busch Stadium against the St. Louis Cardinals Tuesday.