Iran launched dozens of ballistic missiles toward Israel on Friday night in retaliation for Israel's surprise attack early Friday. Israel struck at the heart of the Iran's nuclear program, killing several nuclear scientists as well as high-ranking military leaders, according to Israeli officials.

A series of loud explosions are heard in central Israel as the military says it carried out intelligence-based strikes in Tehran.

Residents awoke to mostly quiet streets in Tel Aviv after spending the night running back and forth to bomb shelters after Iran’s attacks on the coastal city. Some restaurants and cafes were closed, although those that remained open were full of people drinking coffee and eating pastries as normal.

Iran fired a new wave of missiles at Israel on Saturday, injuring several people in residential buildings, as Israel said it was striking Tehran in response.

View of Tel Aviv skyline as Israel strikes Iran’s nuclear sites and kills top generals ISRAEL has launched devastating air strikes against Iran in a dramatic escalation risking all-out nuclear war in the Middle East.

Onlookers gathered on Saturday at a central Tel Aviv residential building next door to Israel’s defense headquarters that was damaged after it took a hit from what appeared to be shrapnel from an overnight missile barrage from Iran.

The Iranian and Israeli strikes mark the most sustained, direct attacks ever between the two rivals. Three people were killed in Israel and at least 78 in Iran, officials said.

Iran crossed "red lines" when it fired missiles at civilians in Israel, Israeli Defense Minister Israel Katz said in a statement Friday evening. Israeli Prime Minister Benjamin Netanyahu said "more is on the way," in a statement Friday evening when talking about Israel's attacks on Iran.

It contains a range of sophisticated centrifuges, including the most advanced models, for enriching uranium to high levels. The International Atomic Energy Agency, the U.N. nuclear watchdog, says there are nearly 14,000 centrifuges at work there, with thousands more in place but inactive.